N-(1H-Indol-3-ylmethylidene)-4-methylpiperazin-1-amine
نویسندگان
چکیده
In the title compound, C14H18N4, the piperazine ring is in a slightly distorted chair conformation. The indole ring system is twisted from the piperazine ring, making a dihedral angle of 7.27 (11)°. In the crystal, N-H⋯N hydrogen bonds link mol-ecules into chains along [10-1].
منابع مشابه
Benzyl N′-(1-methyl-1H-indol-3-ylmethylidene)hydrazinecarbodithioate
The N'-(1-methyl-1H-indol-3-ylmethyl-idene)hydrazine-carbo-dithio-ate portion of the title mol-ecule, C(18)H(17)N(3)S(2), is nearly planar; this unit and the phenyl ring subtend an angle of 112.9 (2)° at the methyl-ene C atom.
متن کاملN-Methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine, a new cholinesterase and monoamine oxidase dual inhibitor.
On the basis of N-((5-(3-(1-benzylpiperidin-4-yl)propoxy)-1-methyl-1H-indol-2-yl)methyl)-N-methylprop-2-yn-1-amine (II, ASS234) and QSAR predictions, in this work we have designed, synthesized, and evaluated a number of new indole derivatives from which we have identified N-methyl-N-((1-methyl-5-(3-(1-(2-methylbenzyl)piperidin-4-yl)propoxy)-1H-indol-2-yl)methyl)prop-2-yn-1-amine (2, MBA236) as ...
متن کامل3,4,5-Trihydroxy-N′-(1H-indol-3-ylmethylidene)benzohydrazide pentahydrate
The two aromatic parts of the title compound, C(16)H(13)N(3)O(4)·5H(2)O, are connected through a conjugated -CH=N-NH-C(O)- fragment, giving an almost planar mol-ecule. The organic mol-ecules and uncoordinated water mol-ecules are linked by N-H⋯O and O-H⋯O hydrogen bonds into a three-dimensional network.
متن کامل2-Hydroxy-5-[(E)-(1H-indol-3-ylmethylidene)azaniumyl]benzoate
The zwitterionic title compound, C(16)H(12)N(2)O(3), was obtained as a result of the condensation of 5-amino-salicylic acid and 1H-indole-3-carbaldehyde. The whole mol-ecule is roughly planar: the 4-hy-droxy-anilinic group and the 1H-indole-3-carbaldehyde moieties are only slightly twisted, making a dihedral angle of 7.77 (11)°, whereas, the carboxyl-ate group makes a dihedral angle of 3.34 (45...
متن کامل4,6-Dimethoxypyrimidin-2-amine–2-(1H-indol-3-yl)acetic acid (1/1)
In the title co-crystal C(6)H(9)N(3)O(2)·C(10)H(9)NO(2), the 4,6-dimeth-oxy-pyrimidin-2-amine mol-ecule inter-acts with the carboxyl group of the 2-(1H-indol-3-yl)acetic acid mol-ecule through N-H⋯O and O-H⋯N hydrogen bonds, forming a cyclic hydrogen-bonded R(2) (2)(8) motif, which is further linked by an N-H⋯N hydrogen bond, forming a supra-molecular chain along the c axis. Neighboring chains ...
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